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Cipro IV
Ciprofloxacin
$20.00
1 bottle · 1 days supply
BrandBranded medicine· By Cooper Pharmaceuticals
$600.00 per month
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Annual cost
$7300a year at this pack size
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FDA boxed warningSerious adverse reactions including tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects and exacerbation of myasthenia gravis
Fluoroquinolones, including Ciprofloxacin Injection (in 5% Dextrose Injection), have been associated with disabling and potentially irreversible serious adverse reactions that have occurred together
including:
Tendinitis and tendon rupture
Peripheral neuropathy
Central nervous system effects
, reserve Ciprofloxacin Injection (in 5% Dextrose Injection) for use in patients who have no alternative treatment options for the following indications:
Acute exacerbation of chronic bronchitis
Acute Sinusitis
About Cipro IV
Overview
Cipro IV contains ciprofloxacin, a fluoroquinolone antibiotic given by intravenous infusion. It is used in adults to treat certain bacterial infections, including urinary tract, lower respiratory tract, skin, bone and joint infections. It works by acting against bacteria that are susceptible to ciprofloxacin.
What it treats
In adults, Cipro IV is used for infections caused by susceptible bacteria, including: - Skin and skin structure infections - Bone and joint infections - Complicated infections within the abdomen - Hospital-acquired pneumonia - Suspected bacterial infection in patients with fever and low neutrophil counts - Chronic bacterial prostatitis - Lower respiratory tract infections, including acute worsening of chronic bronchitis - Urinary tract infections - Acute sinusitis It is also used in adults and children for inhalational anthrax after exposure and for plague, and in children for complicated urinary tract infections and kidney infections (pyelonephritis).
Safety information
Side effects
Common side effects include nausea, diarrhea, vomiting, headache, restlessness, rash, reactions at the intravenous site, abnormal liver test results, nervous system disturbances, and increased levels of eosinophils, a type of white blood cell. Serious side effects can be disabling and potentially permanent. Contact a doctor immediately for tendon inflammation or rupture, nerve damage, effects on the brain or nervous system, worsening of myasthenia gravis, liver injury, or severe allergic reactions. Serious allergic reactions can be fatal and may occur after the first or a later dose. Ciprofloxacin must be stopped at the first sign of a skin rash, jaundice (yellowing of the skin or eyes), or another sign of an allergic reaction, and immediately if symptoms of hepatitis occur. Other serious risks requiring prompt medical attention include Clostridioides difficile-associated diarrhea or inflammation of the colon, abnormal heart rhythms due to QT prolongation, and an aortic aneurysm or dissection (bulging or tearing of the body’s main artery). Serious reactions can also occur when ciprofloxacin is used with theophylline. Muscle and joint problems in children and increased sensitivity to sunlight have also been reported.
FDA boxed warning
Serious adverse reactions including tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects and exacerbation of myasthenia gravis
Fluoroquinolones, including Ciprofloxacin Injection (in 5% Dextrose Injection), have been associated with disabling and potentially irreversible serious adverse reactions that have occurred together
including:
Tendinitis and tendon rupture
Peripheral neuropathy
Central nervous system effects
, reserve Ciprofloxacin Injection (in 5% Dextrose Injection) for use in patients who have no alternative treatment options for the following indications:
Acute exacerbation of chronic bronchitis
Acute Sinusitis
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not use Cipro IV if you have a known allergy to ciprofloxacin or other quinolone antibiotics, or if you are taking tizanidine. Avoid use if you have a known prolonged QT interval (a heart rhythm abnormality), low blood potassium, or are taking other medicines that prolong the QT interval. Serious, sometimes fatal allergic reactions can occur after the first or later doses. Treatment must be stopped at the first sign of a skin rash, jaundice (yellowing of the skin or eyes), or another sign of an allergic reaction. Stop treatment immediately if signs or symptoms of hepatitis develop. Diarrhea associated with Clostridioides difficile can occur; symptoms of colitis require medical assessment. Breastfeeding is not recommended during treatment. Breast milk may be expressed and discarded during treatment and for two days after the last dose. If treatment is for inhalational anthrax after exposure, the risks and benefits of continuing breastfeeding should be considered.
Interactions
Cipro IV (ciprofloxacin) can affect the levels or effects of other medicines. Do not use it with tizanidine, as this combination can increase low blood pressure and sedation. Avoid combining it with theophylline, duloxetine or zolpidem. Serious and fatal reactions have been reported with theophylline. If theophylline or duloxetine cannot be avoided, close monitoring is needed. Avoid use with medicines that prolong the QT interval, an electrical timing measure of the heartbeat. These include certain heart rhythm medicines, tricyclic antidepressants, macrolide antibiotics and antipsychotics. Tell your doctor if you use: • Oral diabetes medicines, especially glyburide or glimepiride: severe low blood sugar, including fatal cases, has been reported. Blood glucose monitoring is needed. • Warfarin or other oral anticoagulants: their blood-thinning effect may increase. Frequent clotting tests and monitoring for bleeding are needed during and shortly after combined treatment. • Phenytoin: levels may rise or fall, affecting seizure control or causing toxicity. Monitoring is needed during and shortly after combined treatment. • Cyclosporine: kidney function monitoring is needed. • Methotrexate: levels and the risk of toxic effects may increase. • Ropinirole or clozapine: monitoring for side effects is needed during and shortly after combined treatment. • Sildenafil: exposure may increase, requiring monitoring for toxic effects. • Non-steroidal anti-inflammatory drugs (NSAIDs), other than aspirin: seizures have been reported when combined with very high amounts of quinolone antibiotics. • Probenecid: ciprofloxacin levels may increase, raising the risk of toxic effects. Also discuss caffeine and xanthine medicines, including pentoxifylline. Ciprofloxacin can raise their levels and prolong their effects.
Using Cipro IV
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store in the original carton below 25°C, protected from light, unless the pack states refrigeration. Do not freeze. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label CIPROFLOXACIN INJECTION, SOLUTION [SAGENT PHARMACEUTICALS] (DailyMed, retrieved 21 September 2026).
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