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Cleocin

Name: Cleocin
Brand: Pfizer
Availability: InStock

Clindamycin

Prescription required

$136.00

150mg · 8 × 16 capsules · 1 month supply

Brand· By Pfizer

$136.00 per month

Brand or generic

Generic packs carry the same active ingredient at the same strength.

Strength

How long a supply?

1 month$136.00 a monthOne-off$136.00

Supplied from Israel

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Annual cost

$1547a year at this pack size

Prescription required

Upload your prescription after ordering, or send it to our pharmacy team. We dispense only against a valid prescription.

150mg

300mg

FDA boxed warning

WARNING

Clostridioides difficile infection (CDI) has been reported with use of nearly all antibacterial agents, including CLEOCIN HCl and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon, leading to overgrowth of C. difficile.

Because CLEOCIN HCl therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate, as described in the

INDICATIONS AND USAGE

section. It should not be used in patients with nonbacterial infections such as most upper respiratory tract infections.

C. difficile produces toxins A and B, which contribute to the development of CDI. Hypertoxin producing strains of C. difficile cause increased morbidity and mortality, as these infections can be refractory to antimicrobial therapy and may require colectomy. CDI must be considered in all patients who present with diarrhea following antibacterial drug use. Careful medical history is necessary since CDI has been reported to occur over two months after the administration of antibacterial agents.

If CDI is suspected or confirmed, ongoing antibacterial drug use not directed against C. difficile may need to be discontinued. Appropriate fluid and electrolyte management, protein supplementation, antibacterial drug treatment of C. difficile, and surgical evaluation should be instituted as clinically indicated.

Read this with the rest of the clinical information

About Cleocin

Overview

Cleocin HCl capsules contain clindamycin, an antibacterial medicine used to treat certain serious bacterial infections. These include infections of the respiratory tract, skin and soft tissues, bloodstream, abdomen, and female pelvis and genital tract caused by susceptible bacteria. Because of the risk of colitis (inflammation of the colon), the prescriber should consider less toxic alternatives; use is reserved for patients allergic to penicillin or for whom penicillin is unsuitable. Clindamycin slows bacterial growth by stopping bacteria from making proteins they need.

What it treats

Cleocin (clindamycin) capsules are used to treat serious infections caused by susceptible bacteria, including: • Respiratory tract infections, including certain lung infections and lung abscesses. • Skin and soft tissue infections. • Bloodstream infections (septicemia). • Infections within the abdomen, including peritonitis and abscesses. • Infections of the female pelvis and genital tract, including infections of the uterine lining and certain infections after surgery. Because of the risk of colitis, use is reserved for patients allergic to penicillin or for whom penicillin is unsuitable, after considering less toxic alternatives.

Safety information

Side effects

Skin rashes are the most frequently reported side effects of Cleocin (clindamycin). Other reported effects include abdominal pain, nausea, vomiting, diarrhea, an unpleasant or metallic taste, itching, hives and vaginal inflammation. Contact a doctor if diarrhea develops during or after treatment. Clindamycin can cause serious inflammation of the colon, including Clostridioides difficile colitis and pseudomembranous colitis. Seek urgent medical attention for severe allergic reactions, swelling beneath the skin or blistering or peeling skin reactions. Reported reactions include anaphylaxis and shock, severe skin reactions that have sometimes been fatal, and DRESS, a drug reaction involving changes in white blood cells and effects throughout the body. Reduced blood flow to the heart, with or without a heart attack, has also been reported as part of an allergic reaction. Other serious reported effects include inflammation and ulcers of the esophagus, particularly when capsules are taken while lying down or with too little water; jaundice and abnormal liver tests; and acute kidney injury. Inflammation of multiple joints has also been reported. Changes in blood cell counts have been reported, including reduced white blood cells or platelets and increased eosinophils, a type of white blood cell. The label states that a direct link between these blood changes and clindamycin could not be established.

FDA boxed warning

WARNING

INDICATIONS AND USAGE

section. It should not be used in patients with nonbacterial infections such as most upper respiratory tract infections.

A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.

When to call your doctor

- Diarrhea or severe abdominal pain during or after treatment, even more than two months later. - A severe rash, blistering skin or peeling skin. - Sudden swelling of the face, lips or tongue. - Yellowing of the skin or whites of the eyes.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

Do not take Cleocin if you have ever had an allergic reaction to clindamycin or lincomycin.

Interactions

Clindamycin may increase the effects of neuromuscular blocking medicines, so caution is needed if you receive these medicines. Medicines that block the liver enzymes CYP3A4 or CYP3A5 may increase clindamycin levels in the blood. Medicines that increase the activity of these enzymes, such as rifampicin, may lower clindamycin levels and reduce its effectiveness. Tell your doctor about other medicines you take; monitoring for side effects or reduced effectiveness may be needed.

Using Cleocin

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label CLEOCIN HYDROCHLORIDE (CLINDAMYCIN HYDROCHLORIDE) CAPSULE [PHARMACIA & UPJOHN COMPANY LLC] (DailyMed, retrieved 19 September 2026).

Patient information and references

Official and supporting information to read alongside advice from your prescriber or pharmacist.

Patient information leaflet (PDF)

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