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Elelyso
Taliglucerase Alfa
$1675.00
200 Units · 1
BrandBranded medicine· By Pfizer
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FDA boxed warningHypersensitivity reactions including anaphylaxis
Patients treated with enzyme replacement therapies have experienced life‑threatening hypersensitivity reactions, including anaphylaxis. Anaphylaxis has occurred during the early course of enzyme replacement therapy and after extended duration of therapy.
Initiate ELELYSO in a healthcare setting with appropriate medical monitoring and support measures, including access to cardiopulmonary resuscitation equipment. If a severe hypersensitivity reaction (e.g., anaphylaxis) occurs, discontinue ELELYSO and immediately initiate appropriate medical treatment, including use of epinephrine. Inform patients of the symptoms of life‑threatening hypersensitivity reactions, including anaphylaxis and to seek immediate medical care should symptoms occur.
About Elelyso
Overview
Elelyso (taliglucerase alfa) is an enzyme replacement therapy. It is used to treat people aged 4 years and older with a confirmed diagnosis of Type 1 Gaucher disease. It replaces the activity of a deficient enzyme, helping break down a fatty substance called glucocerebroside that builds up in certain cells.
What it treats
Treatment of confirmed Type 1 Gaucher disease in patients aged 4 years and older.
Safety information
Side effects
Common side effects in adults not previously treated include headache, joint pain, tiredness, nausea, dizziness, abdominal pain, itching, flushing, vomiting and hives. In patients who switched from imiglucerase, the most common side effects reported after nine months of treatment were joint pain, headache and pain in the arms or legs.
FDA boxed warning
Hypersensitivity reactions including anaphylaxis
Patients treated with enzyme replacement therapies have experienced life‑threatening hypersensitivity reactions, including anaphylaxis. Anaphylaxis has occurred during the early course of enzyme replacement therapy and after extended duration of therapy.
Initiate ELELYSO in a healthcare setting with appropriate medical monitoring and support measures, including access to cardiopulmonary resuscitation equipment. If a severe hypersensitivity reaction (e.g., anaphylaxis) occurs, discontinue ELELYSO and immediately initiate appropriate medical treatment, including use of epinephrine. Inform patients of the symptoms of life‑threatening hypersensitivity reactions, including anaphylaxis and to seek immediate medical care should symptoms occur.
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Using Elelyso
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store in the original carton below 25°C, protected from light, unless the pack states refrigeration. Do not freeze. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label ELELYSO (TALIGLUCERASE ALFA) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [PFIZER LABORATORIES DIV PFIZER INC] (DailyMed, retrieved 19 September 2026).
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