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Epivir
Lamivodine
$504.00
100mg · 3 × 28 tablets · 3 months supply
BrandBranded medicine· By GSK
$168.00 per month
Strength
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Annual cost
$2184a year at this pack size
Prescription required
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5mg / 1ml
100mg
FDA boxed warningExacerbations of hepatitis b and different formulations of epivir
Exacerbations of Hepatitis B
Important Differences among Lamivudine-Containing Products
EPIVIR tablets and oral solution (used to treat HIV-1 infection) contain a higher dose of the active ingredient (lamivudine) than EPIVIR-HBV tablets and oral solution (used to treat chronic HBV infection). Patients with HIV-1 infection should receive only dosage forms appropriate for treatment of HIV-1.
Patients with HIV-1 infection should receive only dosage forms of EPIVIR appropriate for treatment of HIV-1.
About Epivir
Overview
Epivir contains lamivudine, an antiretroviral medicine. It is used with other antiretroviral medicines to treat human immunodeficiency virus type 1 (HIV-1) infection. It works by blocking an enzyme called reverse transcriptase.
What it treats
Treatment of human immunodeficiency virus type 1 (HIV-1) infection in combination with other antiretroviral medicines. This product is intended for HIV-1, not hepatitis B virus (HBV) infection.
Safety information
Side effects
Commonly reported side effects in adults include headache, nausea, feeling unwell, tiredness, nasal symptoms, diarrhoea and cough. In children, the most commonly reported side effects are fever and cough. Serious reactions include worsening of hepatitis B, a build-up of lactic acid in the blood (lactic acidosis), severe liver enlargement with fat build-up, inflammation of the pancreas (pancreatitis), and immune reconstitution syndrome. Contact a doctor if you suspect a serious reaction. Lactic acidosis and severe liver enlargement with fat build-up have included fatal cases. Particular caution is needed in children with a history of pancreatitis or other significant risk factors for it.
FDA boxed warning
Exacerbations of hepatitis b and different formulations of epivir
Exacerbations of Hepatitis B
Important Differences among Lamivudine-Containing Products
EPIVIR tablets and oral solution (used to treat HIV-1 infection) contain a higher dose of the active ingredient (lamivudine) than EPIVIR-HBV tablets and oral solution (used to treat chronic HBV infection). Patients with HIV-1 infection should receive only dosage forms appropriate for treatment of HIV-1.
Patients with HIV-1 infection should receive only dosage forms of EPIVIR appropriate for treatment of HIV-1.
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
Before taking this medicine
Do not take Epivir if you have previously had an allergic reaction to lamivudine. Caution is needed in people with both HIV-1 and hepatitis B, as hepatitis B virus resistant to lamivudine has been reported during treatment. Children with a history of pancreatitis or significant risk factors for it also require caution; treatment may need to be stopped if clinically appropriate. Lactic acidosis (a buildup of lactic acid in the blood) and severe liver enlargement with fat accumulation, including fatal cases, have been reported with nucleoside analogue medicines. Immune reconstitution syndrome, an inflammatory response as the immune system recovers, has been reported with combination antiretroviral treatment. Women with HIV should not breastfeed because of the risk of transmitting HIV.
Interactions
Sorbitol may reduce lamivudine levels in the body. Tell your doctor if you use products containing sorbitol. Regular use together should be avoided when possible.
Using Epivir
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label EPIVIR (LAMIVUDINE) TABLET, FILM COATED EPIVIR (LAMIVUDINE) SOLUTION [VIIV HEALTHCARE COMPANY] (DailyMed, retrieved 19 September 2026).
Patient information and references
Official and supporting information to read alongside advice from your prescriber or pharmacist.
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