Farxiga

Before taking this medicine

Do not take Farxiga if you have had a serious allergic reaction to dapagliflozin or any of its other ingredients. Reported reactions include anaphylaxis and angioedema (swelling). Farxiga requires caution in people at risk of ketoacidosis, including those with type 1 diabetes. Ketoacidosis can occur regardless of blood glucose levels. Ketone monitoring may be needed. If ketoacidosis is suspected, Farxiga must be stopped and the condition assessed; it should not be restarted until ketoacidosis has resolved. Older adults, people with kidney impairment or low systolic blood pressure, and those taking diuretics need assessment of fluid levels and kidney function before treatment, with monitoring during treatment. Older adults have a higher risk of low-blood-pressure-related side effects, while people with kidney impairment have a higher risk of fluid-depletion-related side effects. Urinary and genital infections require prompt assessment and treatment. These can include serious urinary infections, kidney infections, genital fungal infections and a rare severe infection around the genitals or perineum called Fournier’s gangrene. Seek immediate medical assessment for pain, tenderness, redness or swelling in this area together with fever or feeling unwell. Farxiga must be stopped if Fournier’s gangrene is suspected. Using Farxiga with insulin or medicines that stimulate insulin release increases the risk of low blood sugar. Farxiga may pose a risk to the fetus during pregnancy, especially in the second and third trimesters. It is not recommended while breastfeeding.