Humalog, illustration of injection pen form (not a photo of the actual pack)

Illustrative image.

Humalog

Insulin

Prescription required

$660.00

200iu/mL · 3 × 5 pen · 3 months supply

BrandBranded medicine· By Lilly

$220.00 per month

Strength

How long a supply?

1 month$220.00 a month
3 months$220.00 a month
6 months$220.00 a month
Supplied from Canada

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Annual cost

$2640a year at this pack size

Prescription required

Upload your prescription after ordering, or send it to our pharmacy team. We dispense only against a valid prescription.

100IU/ml

200iu/mL

About Humalog

Overview

Humalog contains insulin lispro, a rapid-acting form of human insulin. It is used to improve blood sugar control in adults and children with diabetes. It works by helping muscle and fat cells take up sugar from the blood and reducing the amount of sugar the liver produces.

What it treats

To improve blood sugar control in adults and children with diabetes mellitus.

Safety information

Side effects

Side effects reported with Humalog include low blood sugar, allergic reactions, reactions at the injection site, changes in fatty tissue under the skin, itching and rash. Low blood sugar can be life-threatening. Severe allergic reactions and low blood potassium can also be life-threatening and require urgent medical attention. Contact a doctor if you experience signs of heart failure; fluid retention and heart failure can occur when Humalog is used with medicines called thiazolidinediones (TZDs). Changes to your insulin treatment can cause high or low blood sugar and should be made under close medical supervision with more frequent blood sugar checks. Insulin mix-ups can cause severe low blood sugar. Check the insulin label before every injection, and never transfer Humalog U-200 from a prefilled pen into a syringe, as this can cause an overdose. Insulin pump malfunction can cause high blood sugar and ketoacidosis, which require medical attention.

When to call your doctor

- Seek immediate medical help for severe low blood sugar. - Seek immediate medical help for a suspected serious allergic reaction, which may include rash or itching.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

Do not use Humalog during an episode of low blood sugar (hypoglycemia), or if you are allergic to insulin lispro or any other ingredient in Humalog. Extra caution and more frequent blood sugar checks are needed if you have kidney or liver problems, do not recognise the warning signs of low blood sugar, or have changes in meals, physical activity or medicines that lower blood sugar. Changes to your insulin treatment or injection site should be made under close medical supervision, as they can cause high or low blood sugar. Severe low blood sugar can be life-threatening. Check the insulin label before every injection to avoid mix-ups. Never transfer Humalog U-200 from a prefilled pen into a syringe, as this can cause an overdose and severe low blood sugar. Never share pens or syringes, even if the needle is changed. Humalog can cause life-threatening allergic reactions and low potassium levels. Stop using Humalog and seek urgent medical help if a serious allergic reaction occurs. People at risk of low potassium may need potassium monitoring. Taking Humalog with thiazolidinediones (TZDs) can cause fluid retention and heart failure and requires monitoring. If an insulin pump malfunctions, high blood sugar and ketoacidosis can occur.

Interactions

Other medicines can change how Humalog affects blood sugar: Medicines that may increase the risk of low blood sugar include other diabetes medicines, ACE inhibitors, angiotensin II receptor blockers, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs such as octreotide, and sulfonamide antibiotics. Medicines that may reduce Humalog’s blood sugar-lowering effect include atypical antipsychotics such as olanzapine and clozapine, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens, protease inhibitors, somatropin, sympathomimetic medicines such as albuterol, epinephrine and terbutaline, and thyroid hormones. Alcohol, beta-blockers, clonidine and lithium salts may either increase or decrease Humalog’s blood sugar-lowering effect. Pentamidine may cause low blood sugar, sometimes followed by high blood sugar. Beta-blockers, clonidine, guanethidine and reserpine may make the warning signs of low blood sugar less noticeable. Discuss these interactions with your doctor. More frequent blood sugar checks may be needed, and your prescriber may need to adjust your treatment.

Using Humalog

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store in the original carton to protect it from light. Check the pack for whether it must be refrigerated before first use and how long it may be kept at room temperature afterwards. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label HUMALOG (INSULIN LISPRO) INJECTION, SOLUTION HUMALOG KWIKPEN (INSULIN LISPRO) INJECTION, SOLUTION HUMALOG JUNIOR KWIKPEN (INSULIN LISPRO) INJECTION, SOLUTION HUMALOG TEMPO PEN (INSULIN LISPRO) INJECTION, SOLUTION STERILE DILUENT (DILUENT) INJECTION, SOLUTION [ELI LILLY AND COMPANY] (DailyMed, retrieved 19 September 2026).

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