Nizoral, illustration of cream tube form (not a photo of the actual pack)

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Nizoral

Ketoconazole

Prescription required

$18.00

20 mg/g - 15 gr · 1 cream

BrandBranded medicine· By Janssen Cilag

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20 mg/g - 100ml

20 mg/g - 15 gr

FDA boxed warning

WARNING

Because ketoconazole tablets have been associated with serious adverse reactions (see

Ketoconazole tablets should be used only when other effective antifungal therapy is not available or tolerated and the potential benefits are considered to outweigh the potential risks.

Hepatotoxicity

WARNINGS section.

QT Prolongation and Drug Interactions Leading to QT Prolongation

Co-administration of the following drugs with ketoconazole is contraindicated: dofetilide, quinidine, pimozide, lurasidone, cisapride, methadone, disopyramide, dronedarone, ranolazine. Ketoconazole can cause elevated plasma concentrations of these drugs and may prolong QT intervals, sometimes resulting in life-threatening ventricular dysrhythmias such as torsades de pointes. See

CONTRAINDICATIONS,

WARNINGS, and

PRECAUTIONS: DRUG INTERACTIONS sections.

Read this with the rest of the clinical information

About Nizoral

Overview

Ketoconazole tablets are an oral antifungal medicine. They treat certain systemic fungal infections: blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis and paracoccidioidomycosis. They are reserved for patients whose other treatments have failed or cannot be tolerated, when the potential benefits outweigh the risks. These tablets are not indicated for fungal nail infections, dermatophyte skin infections or Candida infections, and should not be used for fungal meningitis.

What it treats

Ketoconazole tablets are used for these systemic fungal infections when other effective antifungal treatments have failed, are unavailable or cannot be tolerated, and the potential benefits outweigh the risks: - Blastomycosis - Coccidioidomycosis - Histoplasmosis - Chromomycosis - Paracoccidioidomycosis The tablets are not indicated for fungal nail infections, dermatophyte skin infections or Candida infections, and should not be used for fungal meningitis.

Safety information

FDA boxed warning

WARNING

Because ketoconazole tablets have been associated with serious adverse reactions (see

Ketoconazole tablets should be used only when other effective antifungal therapy is not available or tolerated and the potential benefits are considered to outweigh the potential risks.

Hepatotoxicity

WARNINGS section.

QT Prolongation and Drug Interactions Leading to QT Prolongation

Co-administration of the following drugs with ketoconazole is contraindicated: dofetilide, quinidine, pimozide, lurasidone, cisapride, methadone, disopyramide, dronedarone, ranolazine. Ketoconazole can cause elevated plasma concentrations of these drugs and may prolong QT intervals, sometimes resulting in life-threatening ventricular dysrhythmias such as torsades de pointes. See

CONTRAINDICATIONS,

WARNINGS, and

PRECAUTIONS: DRUG INTERACTIONS sections.

A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.

When to call your doctor

- Seek immediate medical attention for yellowing of your skin or the whites of your eyes. - Seek immediate medical attention for sudden swelling of your face, lips or tongue. - Seek immediate medical attention for a fast or irregular heartbeat. - Seek immediate medical attention for a widespread rash with pus-filled bumps.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Interactions

Ketoconazole tablets can increase the levels of certain medicines in the blood, causing serious side effects, including potentially fatal abnormal heart rhythms. Do not take ketoconazole tablets with dofetilide, quinidine, cisapride, pimozide, methadone, disopyramide, dronedarone, lurasidone, irinotecan, felodipine, nisoldipine, ranolazine, tolvaptan, eplerenone or colchicine. Other combinations that must not be used include: • Oral midazolam, oral triazolam or alprazolam, because their sedative effects can become stronger and last longer. • Simvastatin or lovastatin, because of the risk of muscle damage. • Ergot medicines, including dihydroergotamine, ergometrine, ergotamine and methylergometrine, because of the risk of ergot toxicity. Tell your doctor if you take any of these medicines before starting ketoconazole tablets.

Using Nizoral

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store below 25°C with the cap closed, away from direct light and heat. Do not freeze. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label KETOCONAZOLE TABLET [AMERISYN LLC] (DailyMed, retrieved 19 September 2026).

Patient information and references

Official and supporting information to read alongside advice from your prescriber or pharmacist.

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