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Sinemet CR
Carbidopa and Levodopa
$93.00
10/100mg · 3 × 100 tablets · 3 months supply
Brand· By Merck
$31.00 per month
Brand or generic
Generic packs carry the same active ingredient at the same strength.
Strength
How long a supply?
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Annual cost
$341a year at this pack size
Prescription required
Upload your prescription after ordering, or send it to our pharmacy team. We dispense only against a valid prescription.
25mg/250mg
50mg / 200mg
10/100mg
25/100mg
25/250mg
About Sinemet CR
What it treats
- Parkinson’s disease - Parkinsonism following encephalitis - Symptomatic parkinsonism that may follow carbon monoxide or manganese poisoning
Safety information
Side effects
The most commonly reported side effects of carbidopa/levodopa tablets are nausea and uncontrolled movements, such as twitching, twisting or writhing. Other reported side effects include dizziness, sleepiness, vomiting, constipation, diarrhoea, dry mouth, headache, sleep problems and nightmares. Contact a doctor promptly if you develop hallucinations, confusion, unusual beliefs, new or worsening depression, compulsive gambling, increased sexual urges or other difficult-to-control urges. Uncontrolled movements that develop or worsen also need medical review. Seek urgent medical help for chest pain, fainting, an irregular heartbeat, seizures, thoughts of suicide, gastrointestinal bleeding, or signs of a serious allergic reaction such as swelling or blistering skin. Sudden sleep episodes during everyday activities can occur and require prompt medical advice. Do not stop treatment suddenly or reduce it rapidly without your prescriber’s advice. This can cause very high fever and confusion. Other serious risks listed in the label include vitamin B6 deficiency, ulcers, glaucoma and blood cell disorders.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Interactions
Iron salts, including iron supplements, and dopamine D2 antagonists, including metoclopramide, may reduce the effectiveness of carbidopa and levodopa. Tell your doctor if you take any of these.
Using Sinemet CR
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label DHIVY (CARBIDOPA LEVODOPA) TABLET [AVION PHARMACEUTICALS, LLC] (DailyMed, retrieved 19 September 2026).
Patient information and references
Official and supporting information to read alongside advice from your prescriber or pharmacist.
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