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Bumex
Bumetanide
$60.00
1mg · 3 × 28 tablets · 3 months supply
Generic
$20.00 per month
Brand or generic
Generic packs carry the same active ingredient at the same strength.
Strength
How long a supply?
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Annual cost
$260a year at this pack size
Prescription required
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1mg
5mg
FDA boxed warning
WARNING
Bumex
® (bumetanide) is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical supervision is required, and dose and dosage schedule have to be adjusted to the individual patient's needs
(see
DOSAGE AND ADMINISTRATION )
About Bumex
Overview
Bumex tablets contain bumetanide, a loop diuretic often called a water pill. They treat fluid buildup (edema) associated with congestive heart failure, liver disease and kidney disease, including nephrotic syndrome. Bumetanide increases urine output to help the body remove excess fluid.
What it treats
- Fluid retention (edema) associated with congestive heart failure. - Fluid retention associated with liver disease. - Fluid retention associated with kidney disease, including nephrotic syndrome.
Safety information
Side effects
The most frequently reported side effects of Bumex include muscle cramps, dizziness, low blood pressure, headache and nausea. Other reported effects include itching, hives, rash, weakness, abdominal pain, vomiting, diarrhea, fatigue, and joint or muscle pain. Serious reported effects include severe skin reactions such as Stevens–Johnson syndrome and toxic epidermal necrolysis, kidney failure, dehydration, hearing impairment, and encephalopathy (impaired brain function) in people with pre-existing liver disease. Contact a doctor if you develop a skin reaction, hearing changes, chest pain or changes in brain function. Bumex can also cause low blood levels of potassium, sodium and chloride, as well as increased uric acid, blood sugar and markers of kidney function. Low platelet counts and other blood-test abnormalities have also been reported. These changes may need medical assessment even when they do not cause noticeable symptoms.
FDA boxed warning
WARNING
Bumex
® (bumetanide) is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical supervision is required, and dose and dosage schedule have to be adjusted to the individual patient's needs
(see
DOSAGE AND ADMINISTRATION )
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take Bumex if you are unable to produce urine (anuria), are allergic to bumetanide, are in a coma caused by liver disease, or have severe depletion of electrolytes (body salts). Liver-related coma or severe electrolyte depletion must improve or be corrected before treatment. In people with progressive kidney disease, treatment must be stopped if blood urea nitrogen or creatinine levels rise markedly, or if urine output becomes very low (oliguria).
Interactions
Bumex should generally not be taken with lithium because it reduces lithium clearance by the kidneys, increasing the risk of lithium toxicity. Medicines known to harm the kidneys should also be avoided with Bumex. Probenecid should not be taken with Bumex, and indomethacin is not recommended alongside it, because both can reduce its effects. Bumex may increase the effects of blood pressure medicines. Your doctor may need to adjust those medicines. Human interaction studies found no effect on digoxin blood levels, warfarin metabolism or blood prothrombin activity, a measure related to clotting.
Using Bumex
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label BUMEX (BUMETANIDE) TABLET [VALIDUS PHARMACEUTICALS LLC] (DailyMed, retrieved 19 September 2026).
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