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Colazal
Balsalazide Disodium
$192.00
750mg · 2 × 130 capsules · 3 months supply
BrandBranded medicine
$64.00 per month
How long a supply?
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Annual cost
$768a year at this pack size
Prescription required
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About Colazal
Overview
Colazal contains balsalazide disodium, an aminosalicylate medicine supplied as capsules. It is used to treat mildly to moderately active ulcerative colitis in adults and children aged 5 years and older. Bacteria in the colon break it down to release mesalamine, which is thought to reduce inflammation locally in the colon. Safety and effectiveness beyond 8 weeks in children aged 5–17 and 12 weeks in adults have not been established.
What it treats
Mildly to moderately active ulcerative colitis in adults and children aged 5 years and older.
Safety information
Side effects
Common side effects include headache, abdominal pain, diarrhea, nausea, vomiting, respiratory infections and joint pain. Side effects in children were similar to those in adults. Serious reactions include kidney problems, kidney stones, liver failure, severe skin reactions and allergic reactions, including inflammation of the heart muscle or the lining around the heart. Stop taking Colazal and seek immediate medical advice if you develop signs of a severe skin reaction or an allergic reaction. Contact your doctor promptly if your ulcerative colitis symptoms worsen. An acute intolerance reaction can be difficult to distinguish from a flare-up and requires stopping treatment if suspected. Kidney function should be checked before and during treatment. Increased sensitivity to sunlight can occur. If you have an existing skin condition, avoid sun exposure, wear protective clothing and use broad-spectrum sunscreen outdoors. Drink adequate fluids during treatment because kidney stones can occur.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take Colazal if you have a known or suspected allergy to salicylates, aminosalicylates, any capsule ingredient, or substances formed when balsalazide breaks down in the body. It should also be avoided if you have pyloric stenosis or another structural or functional blockage in the upper digestive tract. Tell your prescriber if you have kidney or liver problems, or take medicines that can harm the kidneys. Kidney function should be checked before and during treatment; treatment should be stopped if it worsens. Older adults have a higher risk of blood disorders and need blood cell and platelet monitoring. Worsening bowel symptoms may indicate an acute intolerance reaction that can resemble a flare of ulcerative colitis. Contact your prescriber promptly if symptoms worsen. Stop treatment and seek immediate medical assessment if an allergic reaction or signs of a severe skin reaction develop. Allergic reactions can include inflammation of the heart muscle or its surrounding lining. If you have an existing skin condition, avoid sun exposure, wear protective clothing and use broad-spectrum sunscreen outdoors. Maintain adequate fluid intake during treatment because kidney stones can occur; these stones may not appear on standard X-rays or CT scans. Tell the clinician ordering urine tests that you take this medicine, as it can falsely raise results for urinary normetanephrine with certain testing methods.
Interactions
Tell your doctor if you take NSAIDs or other medicines that can harm the kidneys. Combining them with balsalazide may increase the risk of kidney damage. Your doctor should monitor kidney function and watch for mesalamine-related side effects. Azathioprine or 6-mercaptopurine may increase the risk of blood disorders when taken with balsalazide. Your doctor should monitor complete blood cell counts and platelet counts.
Using Colazal
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label BALSALAZIDE DISODIUM CAPSULE [APOTEX CORP.] (DailyMed, retrieved 19 September 2026).
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