Contrave, illustration of tablet form (not a photo of the actual pack)

Illustrative image.

Contrave

Bupropion Hydrochloride - Naltrexone Hydrochloride

Prescription required

$699.00

90/8mg · 3 × 112 tablets · 6 months supply

BrandBranded medicine

$116.50 per month

How long a supply?

6 months$116.50 a month
Supplied from UK

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Annual cost

$1631a year at this pack size

Prescription required

Upload your prescription after ordering, or send it to our pharmacy team. We dispense only against a valid prescription.

90/8mg

FDA boxed warningSuicidal thoughts and behaviors

SUICIDALITY AND ANTIDEPRESSANT DRUGS

Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term trials. These trials did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in subjects aged 65 and older

In patients of all ages who are started on antidepressant therapy, monitor closely for worsening, and for emergence of suicidal thoughts and behaviors. Advise families and caregivers of the need for close observation and communication with the prescriber

Increased risk of suicidal thinking and behavior in children, adolescents, and young adults taking antidepressants.

Monitor for worsening and emergence of suicidal thoughts and behaviors.

Read this with the rest of the clinical information

Safety information

Side effects

The supplied bupropion label lists common side effects including dry mouth, nausea, trouble sleeping, dizziness, sore throat, abdominal pain, agitation, anxiety, shaking, palpitations, sweating, ringing in the ears, muscle pain, loss of appetite, frequent urination and rash. Serious risks include seizures, increased blood pressure, mania or hypomania, psychosis, angle-closure glaucoma and hypersensitivity reactions. Contact a doctor promptly if serious reactions occur. Stop treatment and seek medical help if a seizure occurs. Blood pressure should be checked before and periodically during treatment. The label also warns about suicidal thoughts and behaviour in children, adolescents and young adults. Serious changes in mood, thinking or behaviour have been reported during bupropion treatment for smoking cessation, including hallucinations, paranoia, aggression, panic and suicidal thoughts or actions. The label advises stopping treatment and contacting a healthcare professional if these symptoms occur. Suicidal thoughts or behaviour warrant immediate medical help. This extract is for bupropion alone, not the bupropion–naltrexone combination in Contrave. It does not provide a complete side-effect profile for Contrave.

FDA boxed warning

Suicidal thoughts and behaviors

SUICIDALITY AND ANTIDEPRESSANT DRUGS

Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term trials. These trials did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in subjects aged 65 and older

In patients of all ages who are started on antidepressant therapy, monitor closely for worsening, and for emergence of suicidal thoughts and behaviors. Advise families and caregivers of the need for close observation and communication with the prescriber

Increased risk of suicidal thinking and behavior in children, adolescents, and young adults taking antidepressants.

Monitor for worsening and emergence of suicidal thoughts and behaviors.

A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.

When to call your doctor

- Seek medical help immediately for thoughts of suicide, self-harm or harming someone else. - Get urgent medical attention if you have a seizure. - Contact your doctor immediately if you see or hear things that are not there, feel intensely suspicious of others or believe things that are not true. - Contact your doctor immediately for new or worsening depression, unusually elevated mood, aggression, severe agitation, anxiety or panic attacks.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Using Contrave

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.

Detailed information for this medicine is being written by our pharmacy team. Pack sizes and pricing are shown alongside.

Clinical information on this page is summarised from the US FDA label BUPROPION HYDROCHLORIDE TABLET [REMEDYREPACK INC.] (DailyMed, retrieved 19 September 2026).

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