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Cozaar
Losartan
$51.00
12.5mg · 3 × 30 tablets · 3 months supply
Generic· By Dexxon
$17.00 per month
Brand or generic
Generic packs carry the same active ingredient at the same strength.
Strength
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Annual cost
$204a year at this pack size
Prescription required
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12.5mg
25mg
50mg
100mg
FDA boxed warningFetal toxicity
When pregnancy is detected, discontinue COZAAR as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.
About Cozaar
Overview
Cozaar contains losartan potassium, an angiotensin II receptor blocker (ARB) used to treat high blood pressure in adults and children older than 6 years. It is also used to reduce stroke risk in people with high blood pressure and an enlarged left ventricle, although evidence indicates this benefit does not apply to Black patients. Cozaar also treats diabetic kidney disease in people with type 2 diabetes, a history of high blood pressure, raised blood creatinine and protein in the urine. It works by blocking the effects of angiotensin II, a substance that narrows blood vessels and stimulates release of the hormone aldosterone.
What it treats
- High blood pressure in adults and children older than 6 years. - Reduction of stroke risk in people with high blood pressure and left ventricular hypertrophy (thickening of the heart’s main pumping chamber). Evidence indicates this benefit does not apply to Black patients. - Diabetic kidney disease in people with type 2 diabetes, a history of high blood pressure, elevated blood creatinine and protein in the urine.
Safety information
Side effects
Common side effects include dizziness, upper respiratory infections, nasal congestion and back pain. Low blood pressure can occur, particularly if your body is low on fluid or salt. Contact your doctor if you develop low blood pressure. Your doctor may also need to monitor your kidney function and potassium levels if you are at risk of problems with either.
FDA boxed warning
Fetal toxicity
When pregnancy is detected, discontinue COZAAR as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take Cozaar if you are allergic to losartan or any other ingredient in the product. If you have diabetes, do not take Cozaar together with aliskiren. Fluid or salt depletion should be corrected before starting Cozaar because of the risk of low blood pressure. Kidney function and potassium levels should be monitored in patients at risk of problems. Liver impairment requires special prescribing consideration. Cozaar is not recommended for children under 6 years of age or for children with a glomerular filtration rate (GFR) below 30 mL/min/1.73 m².
Interactions
Medicines or supplements that raise potassium levels can increase the risk of high blood potassium when taken with Cozaar. Lithium may build up to toxic levels. Nonsteroidal anti-inflammatory drugs (NSAIDs) can increase the risk of kidney problems and reduce Cozaar’s blood-pressure-lowering effect. Combining Cozaar with other medicines that block the renin-angiotensin system can increase the risk of kidney problems, low blood pressure, fainting and high potassium. Rifampin and fluconazole can change the levels of losartan and its active breakdown product in the body. Tell your doctor if you take either medicine.
Using Cozaar
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label COZAAR (LOSARTAN POTASSIUM) TABLET, FILM COATED [ORGANON LLC] (DailyMed, retrieved 19 September 2026).
Patient information and references
Official and supporting information to read alongside advice from your prescriber or pharmacist.
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