Epipen, illustration of injection pen form (not a photo of the actual pack)

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Epipen

Adrenalin (also called Epinephrine)

Prescription required

$253.00

0.15mg · 2 pre-filled pen

GenericGeneric medicine· By Trupharm

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0.15mg

1mg

About Epipen

Overview

EpiPen contains epinephrine and is used for emergency treatment of allergic reactions, including anaphylaxis. These reactions may be triggered by insect stings or bites, foods, medicines or other allergens. It works by stimulating targets in the body called alpha- and beta-adrenergic receptors. EpiPen is an emergency supportive treatment and does not replace immediate medical care.

What it treats

- Emergency treatment of allergic reactions, including anaphylaxis caused by insect stings or bites, foods, medicines, allergen immunotherapy, diagnostic testing substances or other allergens. - Exercise-induced anaphylaxis and anaphylaxis with no known cause. EpiPen provides immediate emergency support and is not a substitute for immediate medical care.

Safety information

Side effects

Common side effects include anxiety, feeling worried or restless, shaking, weakness, dizziness, sweating, a pounding or fluttering heartbeat, pale skin, nausea, vomiting, headache and difficulty breathing. These effects may be more likely in people with high blood pressure or an overactive thyroid. Seek immediate medical or hospital care after using EpiPen. Serious side effects reported include abnormal heart rhythms, including potentially fatal rhythms; bleeding in the brain following a rapid rise in blood pressure; chest pain in people with coronary artery disease; and rare cases of stress-related heart muscle damage. Rare but serious skin and soft tissue infections, including infections that destroy tissue and gas gangrene, have occurred after injection. Seek medical care if signs or symptoms of infection develop. Accidental injection into the fingers, toes, hands or feet can reduce blood flow to the affected area and requires immediate medical attention. It may cause pale or cold skin, reduced sensation or injury. Injection injuries can include bruising, bleeding, cuts, bone injury, or bent or embedded needles, particularly if a young child moves during injection.

When to call your doctor

• Seek emergency medical care immediately after using EpiPen, even if you feel better. • Get immediate medical help for chest pain or a racing, pounding or irregular heartbeat. • Get immediate medical help for difficulty breathing. • Seek immediate care after accidental injection into a finger, toe, hand or foot, especially if the area becomes pale, cold or numb. • Seek medical care if you develop signs of infection at the injection site.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

The label lists no contraindications. Use with caution in people with heart disease, as epinephrine may worsen angina or cause abnormal heart rhythms. Older adults may be at greater risk of side effects. The presence of a sulfite in this product should not deter use. Seek immediate medical or hospital care when using this medicine. Do not inject into a vein, the buttock, fingers, toes, hands or feet. When giving an injection to a young child, hold the child’s leg firmly and limit movement before and during injection to reduce the risk of injury. Rare serious skin and soft tissue infections have been reported after epinephrine injection; seek medical care if signs or symptoms of infection develop.

Interactions

Epinephrine can interact with the following medicines: • Cardiac glycosides, diuretics and medicines for irregular heart rhythms (anti-arrhythmics): careful monitoring for irregular heart rhythms is needed when used with epinephrine. • Tricyclic antidepressants, monoamine oxidase inhibitors (MAOIs), levothyroxine and certain antihistamines, including chlorpheniramine, tripelennamine and diphenhydramine: these may increase epinephrine’s effects. • Beta-blockers, such as propranolol: these can reduce epinephrine’s effects on stimulating the heart and opening the airways. • Alpha-blockers, such as phentolamine: these can reduce epinephrine’s effects on narrowing blood vessels and raising blood pressure. • Ergot alkaloids: these may reverse epinephrine’s blood-pressure-raising effect. Tell your doctor if you take any of these medicines.

Using Epipen

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store in the original carton to protect it from light. Check the pack for whether it must be refrigerated before first use and how long it may be kept at room temperature afterwards. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label EPIPEN (EPINEPHRINE) INJECTION EPIPEN JR (EPINEPHRINE) INJECTION [VIATRIS SPECIALTY LLC] (DailyMed, retrieved 19 September 2026).

Patient information and references

Official and supporting information to read alongside advice from your prescriber or pharmacist.

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