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Fosamax , Fosavance
Alendronate
$141.00
10mg · 3 × 30 tablets · 3 months supply
Brand· By MSD
$47.00 per month
Brand or generic
Generic packs carry the same active ingredient at the same strength.
Strength
How long a supply?
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Annual cost
$564a year at this pack size
Prescription required
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10mg
70 mg / 5,600 IU
70mg
About Fosamax , Fosavance
Overview
Alendronate is a bisphosphonate medicine used to treat and prevent osteoporosis in women after menopause and to increase bone mass in men with osteoporosis. It is also used to treat osteoporosis caused by glucocorticoid medicines and Paget’s disease of bone. It works by slowing the activity of cells that break down bone, reducing bone loss.
What it treats
- Treatment and prevention of osteoporosis in postmenopausal women. - Treatment to increase bone mass in men with osteoporosis. - Treatment of glucocorticoid-induced osteoporosis. - Treatment of Paget’s disease of bone.
Safety information
Side effects
Common side effects include abdominal pain, acid reflux, constipation, diarrhoea, indigestion, nausea, and bone, joint or muscle pain. Serious side effects include upper digestive tract problems, worsening low blood calcium, severe bone, joint or muscle pain, jawbone damage (osteonecrosis), and unusual fractures, including fractures of the thigh bone. Stop taking alendronate and contact your doctor if you develop new or worsening upper digestive tract symptoms or severe bone, joint or muscle pain. Contact your doctor if you develop new thigh or groin pain, as this needs assessment for a possible fracture. Low blood calcium must be corrected before treatment begins.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take alendronate if you have: • Problems with the esophagus (food pipe) that delay emptying, such as narrowing or achalasia. • An inability to stand or sit upright for at least 30 minutes. • Low blood calcium, which must be corrected before treatment. • An allergy to any ingredient in the product. Hives and angioedema (swelling) have been reported. Alendronate is not recommended for people with severe kidney impairment (creatinine clearance below 35 mL/min) and is not indicated for children. Stop taking it if pregnancy is recognized. Alendronate can cause upper digestive tract problems. Follow the prescribed administration instructions and stop taking it if new or worsening symptoms occur. Stop treatment if severe bone, joint or muscle pain develops. Jawbone damage (osteonecrosis) and unusual fractures, including thighbone fractures, have been reported. New thigh or groin pain needs medical assessment to rule out a fracture; your prescriber should reassess whether treatment should continue.
Interactions
Calcium supplements, antacids and other medicines taken by mouth that contain multivalent cations (certain mineral ions) can reduce alendronate absorption. Tell your doctor if you take any of these. Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) may worsen irritation of the digestive tract when used with alendronate. Discuss their use with your doctor.
Using Fosamax , Fosavance
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label ALENDRONATE SODIUM TABLET [REMEDYREPACK INC.] (DailyMed, retrieved 19 September 2026).
Patient information and references
Official and supporting information to read alongside advice from your prescriber or pharmacist.
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