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Inderal
Propranolol
$90.00
10mg · 5 × 50 tablets · 3 months supply
GenericGeneric medicine· By Desitin
$30.00 per month
Strength
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Annual cost
$378a year at this pack size
Prescription required
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10mg
40mg
About Inderal
Overview
Inderal is a prescription tablet containing propranolol, a beta blocker. It is used to treat high blood pressure, angina, a rapid heart rate associated with atrial fibrillation, and hereditary essential tremor, and to prevent migraines, not to treat an attack that has already started. It is also used to reduce the risk of cardiovascular death in clinically stable people who have survived the acute phase of a heart attack. It works by blocking beta receptors, reducing increases in heart rate and the force of heart contractions and generally lowering the heart’s oxygen needs during activity.
What it treats
- High blood pressure, but not hypertensive emergencies. - Angina due to coronary artery disease, to reduce episodes and improve exercise tolerance. - Atrial fibrillation with a rapid heart rate, to control the ventricular rate. - Reduction of cardiovascular mortality after a heart attack in clinically stable patients. - Migraine prevention, not treatment of an attack that has already started. - Familial or hereditary essential tremor, not tremor associated with Parkinsonism. - Symptomatic hypertrophic subaortic stenosis, to improve functional ability. - Pheochromocytoma, alongside alpha-blocker treatment, to control blood pressure and reduce symptoms.
Safety information
Side effects
Reported side effects include light-headedness, tiredness, weakness, difficulty sleeping, vivid dreams, nausea, vomiting, upper stomach discomfort, abdominal cramps, diarrhea and constipation. Other reported effects include dry eyes, vision changes, tingling in the hands, hair loss, rashes, erection problems and Peyronie’s disease (curvature of the penis). The label does not state how common these effects are. Contact a doctor promptly for depression, hallucinations, confusion, disorientation or short-term memory loss. Serious reported effects also include a slow heartbeat, low blood pressure, heart failure, worsening problems with electrical conduction in the heart, and reduced blood flow to the fingers or toes. Blood disorders can include dangerously low levels of certain white blood cells or bleeding into the skin, with or without low platelets. Systemic lupus erythematosus and lupus-like reactions have also been reported. Seek urgent medical attention for severe allergic reactions, breathing distress, or tightening of the airways or throat. Serious skin reactions reported include Stevens–Johnson syndrome, toxic epidermal necrolysis and extensive skin peeling. Fever with aching and a sore throat has also been reported. Other serious effects include a blood clot in an artery supplying the intestines and inflammation of the colon caused by reduced blood flow.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take Inderal (propranolol) if you have cardiogenic shock, a condition in which the heart cannot pump enough blood; a slow heart rhythm called sinus bradycardia; heart block greater than first degree; bronchial asthma; or a known allergy to propranolol hydrochloride. Kidney or liver impairment requires caution because these conditions can increase propranolol levels in the blood. In people with cirrhosis, propranolol also stays in the body longer. Tell your prescriber if you have kidney or liver disease.
Interactions
Propranolol can interact with medicines that affect heart rate, blood pressure or how the body breaks down drugs. Important combinations to discuss with your doctor include: • Heart rhythm medicines, including amiodarone, quinidine, propafenone and lidocaine. Effects on the heart may be increased, and propranolol can raise levels of some of these medicines. Lidocaine toxicity has been reported. • Digitalis medicines and calcium channel blockers, especially verapamil and diltiazem. These combinations can cause an excessively slow heartbeat or problems with the heart’s electrical conduction. Serious low blood pressure and heart failure have also been reported. • Other blood pressure medicines, including ACE inhibitors, prazosin, terazosin, doxazosin and reserpine, which may increase the risk of low blood pressure. Reserpine can also cause a markedly slow heartbeat or fainting. Propranolol may reduce clonidine’s blood-pressure-lowering effect, and particular caution is needed when clonidine is being stopped. • Medicines that may increase propranolol levels or toxicity, including fluoxetine, paroxetine, fluvoxamine, imipramine, ciprofloxacin, fluconazole, isoniazid, ritonavir and cimetidine. MAO inhibitors and tricyclic antidepressants may also increase blood-pressure-lowering effects. • Rifampin, phenytoin, phenobarbital, aluminum hydroxide antacids, cholestyramine and colestipol, which may lower propranolol levels. • Warfarin. Propranolol can increase warfarin levels and prolong blood clotting time, so prothrombin time should be monitored. • Rizatriptan, zolmitriptan, theophylline and diazepam, whose levels may increase with propranolol. • Anti-inflammatory pain medicines such as indomethacin. NSAIDs may reduce propranolol’s blood-pressure-lowering effect. • Chlorpromazine, which can increase propranolol levels, and haloperidol, whose combination with propranolol has been associated with low blood pressure and cardiac arrest. Also raise the use of epinephrine, dobutamine, isoproterenol, anesthetics, thyroxine, lovastatin or pravastatin. Propranolol can alter their effects or levels and may reduce the sensitivity of dobutamine stress echocardiography. Alcohol may increase propranolol levels. Cigarette smoking can lower propranolol levels by increasing how quickly the body clears it.
Using Inderal
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label PROPRANOLOL HYDROCHLORIDE TABLET [PAR HEALTH USA, LLC] (DailyMed, retrieved 19 September 2026).
Patient information and references
Official and supporting information to read alongside advice from your prescriber or pharmacist.
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