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Izervay
Avacincaptad Pegol
$13185.00
20mg/ml · 3 × 1 vial · 3 months supply
BrandBranded medicine· By Astellas Pharma
$4395.00 per month
How long a supply?
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Ships cold, in insulated packing
This medicine ships in insulated packing with coolant and carries its own shipping charge, shown at checkout.
Annual cost
$52740a year at this pack size
Prescription required
Upload your prescription after ordering, or send it to our pharmacy team. We dispense only against a valid prescription.
About Izervay
Overview
Izervay contains avacincaptad pegol and is supplied in a single-dose vial for injection into the eye. It is used to treat geographic atrophy secondary to age-related macular degeneration (AMD). It works by blocking a protein called complement C5, which may reduce the formation of a complex called the membrane attack complex.
What it treats
Geographic atrophy (GA) secondary to age-related macular degeneration (AMD).
Safety information
Side effects
Common side effects include bleeding on the surface of the eye, increased pressure inside the eye, blurred vision, wet age-related macular degeneration, inflammation affecting small areas of the cornea (the clear front surface of the eye), and eye pain. Serious risks include infections in or around the eye, including infection inside the eye (endophthalmitis), inflammation inside the eye, retinal detachment, wet age-related macular degeneration, and increased eye pressure. Contact a doctor promptly if you experience or suspect any of these serious problems.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Izervay must not be used if you have an infection in or around the eye, or active inflammation inside the eye. Warnings include endophthalmitis (a serious infection inside the eye), retinal detachment, neovascular (wet) age-related macular degeneration (AMD), and increased pressure inside the eye.
Using Izervay
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store in the original carton below 25°C, protected from light, unless the pack states refrigeration. Do not freeze. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label IZERVAY (AVACINCAPTAD PEGOL) INJECTION [ASTELLAS PHARMA US, INC.] (DailyMed, retrieved 19 September 2026).
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