Linzess, illustration of capsule form (not a photo of the actual pack)

Illustrative image.

Linzess

Linaclotide

Prescription required

$600.00

72mcg · 3 × 30 capsules · 3 months supply

BrandBranded medicine

$200.00 per month

Strength

How long a supply?

1 month$200.00 a month
3 months$200.00 a month
6 months$200.00 a month
Supplied from Canada

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Annual cost

$2400a year at this pack size

Prescription required

Upload your prescription after ordering, or send it to our pharmacy team. We dispense only against a valid prescription.

72mcg

145mcg

290mcg

FDA boxed warningRisk of serious dehydration in pediatric patients

LESS THAN 2 YEARS OF AGE

LINZESS is contraindicated in patients less than

years of age; in nonclinical studies in neonatal mice, administration of a single, clinically relevant adult oral dose of linaclotide caused deaths due to dehydration

years of age; in neonatal mice, linaclotide caused deaths due to dehydration.

Read this with the rest of the clinical information

About Linzess

Overview

Linzess contains linaclotide, a medicine used to treat certain types of constipation. It treats irritable bowel syndrome with constipation (IBS-C) in adults and children aged 7 years and older, and chronic idiopathic constipation (CIC) in adults. It also treats functional constipation in children aged 2 years and older. It acts locally in the intestine to increase fluid and help bowel contents move through more quickly.

What it treats

• Irritable bowel syndrome with constipation (IBS-C) in adults and children aged 7 years and older. • Chronic idiopathic constipation (CIC) in adults. • Functional constipation (FC) in children aged 2 years and older.

Safety information

Side effects

Common side effects in adults include diarrhea, abdominal pain, gas and bloating. Diarrhea is the most common side effect in children aged 7–17 with irritable bowel syndrome with constipation and aged 6–17 with functional constipation. Diarrhea can be severe. If severe diarrhea occurs, stop taking Linzess and contact a doctor. Rehydration is needed.

FDA boxed warning

Risk of serious dehydration in pediatric patients

LESS THAN 2 YEARS OF AGE

LINZESS is contraindicated in patients less than

years of age; in nonclinical studies in neonatal mice, administration of a single, clinically relevant adult oral dose of linaclotide caused deaths due to dehydration

years of age; in neonatal mice, linaclotide caused deaths due to dehydration.

A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.

When to call your doctor

- Seek medical attention immediately if you have severe diarrhea.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

Do not take Linzess (linaclotide) if you have a known or suspected physical blockage in your stomach or intestines. It must not be given to children younger than 2 years because of the risk of serious dehydration. Linzess can cause severe diarrhea. If this occurs, stop taking it and seek medical advice. Fluids will need to be replaced to address dehydration.

Using Linzess

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label LINZESS (LINACLOTIDE) CAPSULE, GELATIN COATED [ALLERGAN, INC.] (DailyMed, retrieved 19 September 2026).

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