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Linzess
Linaclotide
$600.00
72mcg · 3 × 30 capsules · 3 months supply
BrandBranded medicine
$200.00 per month
Strength
How long a supply?
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Annual cost
$2400a year at this pack size
Prescription required
Upload your prescription after ordering, or send it to our pharmacy team. We dispense only against a valid prescription.
72mcg
145mcg
290mcg
FDA boxed warningRisk of serious dehydration in pediatric patients
LESS THAN 2 YEARS OF AGE
LINZESS is contraindicated in patients less than
years of age; in nonclinical studies in neonatal mice, administration of a single, clinically relevant adult oral dose of linaclotide caused deaths due to dehydration
years of age; in neonatal mice, linaclotide caused deaths due to dehydration.
About Linzess
Overview
Linzess contains linaclotide, a medicine used to treat certain types of constipation. It treats irritable bowel syndrome with constipation (IBS-C) in adults and children aged 7 years and older, and chronic idiopathic constipation (CIC) in adults. It also treats functional constipation in children aged 2 years and older. It acts locally in the intestine to increase fluid and help bowel contents move through more quickly.
What it treats
• Irritable bowel syndrome with constipation (IBS-C) in adults and children aged 7 years and older. • Chronic idiopathic constipation (CIC) in adults. • Functional constipation (FC) in children aged 2 years and older.
Safety information
Side effects
Common side effects in adults include diarrhea, abdominal pain, gas and bloating. Diarrhea is the most common side effect in children aged 7–17 with irritable bowel syndrome with constipation and aged 6–17 with functional constipation. Diarrhea can be severe. If severe diarrhea occurs, stop taking Linzess and contact a doctor. Rehydration is needed.
FDA boxed warning
Risk of serious dehydration in pediatric patients
LESS THAN 2 YEARS OF AGE
LINZESS is contraindicated in patients less than
years of age; in nonclinical studies in neonatal mice, administration of a single, clinically relevant adult oral dose of linaclotide caused deaths due to dehydration
years of age; in neonatal mice, linaclotide caused deaths due to dehydration.
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take Linzess (linaclotide) if you have a known or suspected physical blockage in your stomach or intestines. It must not be given to children younger than 2 years because of the risk of serious dehydration. Linzess can cause severe diarrhea. If this occurs, stop taking it and seek medical advice. Fluids will need to be replaced to address dehydration.
Using Linzess
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label LINZESS (LINACLOTIDE) CAPSULE, GELATIN COATED [ALLERGAN, INC.] (DailyMed, retrieved 19 September 2026).
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