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Methimazole
Methimazole
$105.00
5mg · 5 × 50 tablets · 3 months supply
Brand
$35.00 per month
Brand or generic
Generic packs carry the same active ingredient at the same strength.
Strength
How long a supply?
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Annual cost
$441a year at this pack size
Prescription required
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About Methimazole
Overview
Methimazole is a prescription antithyroid medicine taken as a tablet. It treats an overactive thyroid caused by Graves’ disease or toxic multinodular goiter when surgery or radioactive iodine treatment is not appropriate. It is also used to ease symptoms before thyroid removal surgery or radioactive iodine treatment. As an antithyroid medicine, it works to reduce thyroid activity.
What it treats
- Overactive thyroid (hyperthyroidism) due to Graves’ disease or toxic multinodular goiter when surgery or radioactive iodine treatment is not appropriate. - Symptoms of hyperthyroidism before thyroid surgery or radioactive iodine treatment.
Safety information
Side effects
Reported side effects include rash, hives, itching, nausea, vomiting, upper abdominal discomfort, joint or muscle pain, tingling, loss of taste, unusual hair loss, headache, drowsiness, dizziness or a spinning sensation, swelling, changes in skin colour, nerve inflammation, salivary gland problems and swollen lymph nodes. The label describes these as minor reactions but does not give their frequency. Serious side effects occur less frequently and warrant contacting a doctor. These include: • Reduced production of blood cells, including very low white blood cell counts, low platelets and aplastic anaemia. • Liver inflammation and jaundice (yellowing of the skin or eyes). Jaundice may persist for several weeks after the medicine is stopped. • Inflammation of blood vessels, which can cause severe complications. • An autoimmune reaction involving insulin that can cause low blood sugar and coma. • Drug-related fever, a lupus-like syndrome and reduced levels of a blood-clotting protein. • Kidney inflammation, reported very rarely. • Acute inflammation of the pancreas, reported after the medicine became available for use.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take methimazole if you are allergic to methimazole or any other ingredient in the tablets.
Interactions
Methimazole may increase the effect of oral blood thinners such as warfarin. Your doctor may consider extra blood-clotting tests (PT/INR), especially before surgery. As thyroid levels return to normal, beta blockers, digitalis medicines and theophylline may need review. Digitalis levels may rise, and theophylline may be cleared from the body more slowly. Tell your doctor if you take any of these medicines; your doctor may need to adjust your treatment.
Using Methimazole
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label METHIMAZOLE TABLET [REMEDYREPACK INC.] (DailyMed, retrieved 19 September 2026).
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