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Pulmozyme
Dornase Alfa
$3555.00
2.5mg · 3 × 30 ampoules · 3 months supply
BrandBranded medicine· By Roche
$1185.00 per month
How long a supply?
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Ships cold, in insulated packing
This medicine ships in insulated packing with coolant and carries its own shipping charge, shown at checkout.
Annual cost
$14220a year at this pack size
Prescription required
Upload your prescription after ordering, or send it to our pharmacy team. We dispense only against a valid prescription.
About Pulmozyme
Overview
Pulmozyme (dornase alfa) is a prescription medicine supplied in ampoules for inhalation through a nebulizer. It is used alongside standard therapies to improve lung function in children and adults with cystic fibrosis. It contains an enzyme that breaks down DNA in airway mucus, making the mucus less thick and sticky.
What it treats
- Cystic fibrosis in children and adults, alongside standard therapies, to improve lung function. - In patients with cystic fibrosis whose forced vital capacity (FVC) is at least 40% of predicted, to reduce the risk of respiratory tract infections requiring injected antibiotics.
Safety information
Side effects
Common side effects reported in clinical trials in people with cystic fibrosis include voice changes, sore throat, rash, inflammation of the voice box, chest pain, eye inflammation, nasal inflammation, fever, difficulty breathing and a decrease in lung function measured by forced vital capacity (FVC).
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Interactions
Available data indicate no clinically important drug interactions with Pulmozyme.
Using Pulmozyme
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store in the original carton below 25°C, protected from light. Do not freeze, and use immediately once opened. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label PULMOZYME (DORNASE ALFA) SOLUTION [GENENTECH, INC.] (DailyMed, retrieved 19 September 2026).
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