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Depalept Chrono
Valproic Acid and Sodium Valproate
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FDA boxed warningLife threatening adverse reactions
Hepatotoxicity, including fatalities, usually during the first 6 months of treatment. Children under the age of two years and patients with mitochondrial disorders are at higher risk. Monitor patients closely, and perform serum liver testing prior to therapy and at frequent intervals thereafter
Fetal Risk, particularly neural tube defects, other major malformations, and decreased IQ
Pancreatitis, including fatal hemorrhagic cases
Safety information
FDA boxed warning
Life threatening adverse reactions
Hepatotoxicity, including fatalities, usually during the first 6 months of treatment. Children under the age of two years and patients with mitochondrial disorders are at higher risk. Monitor patients closely, and perform serum liver testing prior to therapy and at frequent intervals thereafter
Fetal Risk, particularly neural tube defects, other major malformations, and decreased IQ
Pancreatitis, including fatal hemorrhagic cases
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
Using Depalept Chrono
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Detailed information for this medicine is being written by our pharmacy team. Pack sizes and pricing are shown alongside.
Clinical information on this page is summarised from the US FDA label VALPROATE SODIUM INJECTION, SOLUTION [SAGENT PHARMACEUTICALS] (DailyMed, retrieved 19 September 2026).
Patient information and references
Official and supporting information to read alongside advice from your prescriber or pharmacist.
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