Engerix‑B, illustration of injection vial form (not a photo of the actual pack)

Illustrative image.

Engerix‑B

Hepatitis B Vaccine (recombinant Hbsag)

Prescription required

$42.00

B · 1 vial

BrandBranded medicine· By GlaxoSmithKline

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About Engerix‑B

Overview

Engerix-B is a recombinant hepatitis B vaccine supplied in a vial for injection into a muscle. It is used to help protect against infection caused by all known subtypes of hepatitis B virus. It helps the body develop protective antibodies against a noninfectious surface protein of the virus.

What it treats

Prevention of infection caused by all known subtypes of hepatitis B virus.

Safety information

Side effects

The most common side effects are soreness at the injection site (22%) and fatigue (14%). Fainting can occur after vaccination and may cause injury. Contact a doctor if fainting occurs. Pauses in breathing (apnea) have been observed after intramuscular vaccination in some infants born prematurely. Seek urgent medical help if this occurs.

When to call your doctor

- Seek medical attention immediately if you faint after vaccination. - Seek medical attention immediately if a baby born prematurely has pauses in breathing after vaccination.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

Do not receive Engerix‑B if you have had a severe allergic reaction, including anaphylaxis, to any previous hepatitis B-containing vaccine or to any ingredient in Engerix‑B, including yeast. Conditions requiring caution include: • Fainting can occur with injectable vaccines. Precautions should be taken to prevent injury from a fall. • Vaccination should be temporarily deferred in infants with a birth weight below 2,000 g whose mothers test negative for hepatitis B surface antigen (HBsAg). • Pauses in breathing have been observed after intramuscular vaccination in some premature infants. The timing of vaccination should be based on the infant’s medical condition and the potential benefits and risks. • People older than 60 years may have a lower antibody response than younger adults.

Using Engerix‑B

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store in the original carton below 25°C, protected from light, unless the pack states refrigeration. Do not freeze. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label ENGERIX-B (HEPATITIS B VACCINE (RECOMBINANT)) INJECTION, SUSPENSION [GLAXOSMITHKLINE BIOLOGICALS SA] (DailyMed, retrieved 19 September 2026).

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