Glassia, illustration of injection vial form (not a photo of the actual pack)

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Glassia

Alpha‑1‑proteinase Inhibitor (human)

Prescription required

$710.00

1gr/50ml · 1 vial

BrandBranded medicine· By Kamada

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About Glassia

Overview

Glassia contains alpha-1-proteinase inhibitor (human), also known as alpha-1-antitrypsin, purified from human plasma. It is used for ongoing replacement and maintenance therapy in adults with clinically evident emphysema caused by severe inherited alpha-1-antitrypsin deficiency. It supplements the deficient protein to help inhibit an enzyme that can break down the walls of the lungs’ air sacs. Its effect on lung flare-ups and the progression of emphysema has not been conclusively demonstrated in randomized, controlled clinical trials.

What it treats

• Long-term replacement and maintenance therapy for adults with clinically evident emphysema caused by severe hereditary alpha-1-antitrypsin (AAT) deficiency.

Safety information

Side effects

The most common side effects reported in clinical trials were headache and upper respiratory infection. Serious reactions include worsening of chronic obstructive pulmonary disease (COPD), which was observed in clinical trials. Contact a doctor if your COPD worsens. Severe allergic reactions, including anaphylaxis, may occur in people with IgA deficiency who have antibodies against IgA, and in those with a history of allergic reactions to other Alpha-1-proteinase inhibitor products. Seek immediate medical help for a severe allergic reaction. Glassia may carry a risk of transmitting infectious agents, including viruses, the variant Creutzfeldt-Jakob disease (vCJD) agent and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent.

When to call your doctor

- Seek medical attention immediately for a severe allergic reaction, including anaphylaxis. - Seek medical attention immediately if your chronic obstructive pulmonary disease (COPD) worsens.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

Do not use Glassia if you have immunoglobulin A (IgA) deficiency with antibodies against IgA, or if you have previously had anaphylaxis or another severe whole-body reaction to an Alpha-1-proteinase inhibitor product. Severe allergic reactions, including anaphylaxis, may occur in people with IgA deficiency and antibodies against IgA, and in those with a history of allergic reactions to other Alpha-1-proteinase inhibitor products. Glassia may carry a risk of transmitting infectious agents, including viruses and the agent that causes variant Creutzfeldt-Jakob disease (vCJD). There is also a theoretical risk of transmitting the Creutzfeldt-Jakob disease (CJD) agent.

Using Glassia

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store in the original carton below 25°C, protected from light, unless the pack states refrigeration. Do not freeze. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label GLASSIA (ALPHA.1-PROTEINASE INHIBITOR HUMAN) INJECTION, SOLUTION [TAKEDA PHARMACEUTICALS AMERICA, INC.] (DailyMed, retrieved 19 September 2026).

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