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Tecfidera
Dimethyl Fumarate
$909.00
240mg · 3 × 56 capsules · 3 months supply
Generic
$303.00 per month
Brand or generic
Generic packs carry the same active ingredient at the same strength.
How long a supply?
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Annual cost
$3939a year at this pack size
Prescription required
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120mg
240mg
About Tecfidera
Overview
Tecfidera contains dimethyl fumarate and comes as delayed-release capsules. It is used to treat relapsing forms of multiple sclerosis (MS) in adults, including clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease. Exactly how it works in MS is unknown, but dimethyl fumarate and its breakdown product activate a pathway involved in how cells respond to oxidative stress.
What it treats
Relapsing forms of multiple sclerosis (MS) in adults, including: - Clinically isolated syndrome - Relapsing-remitting MS - Active secondary progressive MS
Safety information
Side effects
Common side effects of Tecfidera include flushing, abdominal pain, diarrhea and nausea. Contact a doctor promptly for serious side effects, including severe allergic reactions (anaphylaxis and angioedema), progressive multifocal leukoencephalopathy (PML), shingles and other serious opportunistic infections, low lymphocyte counts (lymphopenia), liver injury and serious gastrointestinal reactions. Tecfidera must be stopped and not restarted if anaphylaxis or angioedema occurs. It should be withheld at the first sign or symptom suggestive of PML. Your doctor may also interrupt treatment for a serious infection or persistently low lymphocyte counts. Blood tests are needed before and during treatment to monitor lymphocytes and liver function.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take Tecfidera if you have a known allergy to dimethyl fumarate or any of its other ingredients. Severe allergic reactions, including anaphylaxis and angioedema (swelling), have occurred. If either occurs, stop Tecfidera and do not restart it. Conditions requiring caution include: • Progressive multifocal leukoencephalopathy (PML): withhold Tecfidera at the first sign or symptom suggesting this condition. • Shingles or other serious opportunistic infections: treatment may need to be withheld until a serious infection has resolved. • Low lymphocyte counts: a complete blood count, including lymphocytes, is needed before treatment, after six months, and every six to twelve months thereafter. Persistently very low counts may require treatment interruption. • Liver injury: liver blood tests are needed before treatment and during treatment when clinically indicated. Tecfidera should be stopped if clinically significant liver injury caused by the medicine is suspected.
Using Tecfidera
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label TECFIDERA (DIMETHYL FUMARATE) KIT TECFIDERA (DIMETHYL FUMARATE) CAPSULE [BIOGEN INC.] (DailyMed, retrieved 19 September 2026).
Patient information and references
Official and supporting information to read alongside advice from your prescriber or pharmacist.
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