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Tirzepatide Compound
Tirzepatide
$1050.00
10mg/mL · 3 × 1 vial · 3 months supply
CompoundedCompounded medicine
$350.00 per month
How long a supply?
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Annual cost
$4550a year at this pack size
Prescription required
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10mg/mL
FDA boxed warningRisk of thyroid c-cell tumors
In rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. It is unknown whether ZEPBOUND causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of tirzepatide-induced rodent thyroid C-cell tumors has not been determined
ZEPBOUND is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
. Counsel patients regarding the potential risk for MTC with the use of ZEPBOUND and inform them of symptoms of thyroid tumors (e.g., a mass in the neck, dysphagia, dyspnea, persistent hoarseness). Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with ZEPBOUND
In rats, tirzepatide causes thyroid C-cell tumors. It is unknown whether ZEPBOUND causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as the human relevance of tirzepatide-induced rodent thyroid C-cell tumors has not been determined.
About Tirzepatide Compound
Overview
Tirzepatide is a medicine given by injection under the skin. The supplied Zepbound label describes its use with a reduced-calorie diet and increased physical activity to reduce excess weight and maintain weight loss in adults with obesity, or overweight with at least one weight-related condition. It also covers treatment of moderate to severe obstructive sleep apnea in adults with obesity. Tirzepatide works by activating GIP and GLP-1 receptors involved in regulating appetite and food intake.
What it treats
The supplied Zepbound (tirzepatide) label lists these uses alongside a reduced-calorie diet and increased physical activity: - Reducing excess body weight and maintaining weight loss long term in adults with obesity, or adults with overweight and at least one weight-related health condition. - Treating moderate to severe obstructive sleep apnea in adults with obesity.
Safety information
Side effects
The supplied Zepbound (tirzepatide) label lists common side effects including nausea, diarrhea, vomiting, constipation, abdominal pain, indigestion, injection-site reactions, tiredness, allergic reactions, burping, hair loss and acid reflux. Serious risks include severe stomach or bowel problems, acute kidney injury from dehydration, gallbladder disease, inflammation of the pancreas (pancreatitis), severe allergic reactions, low blood sugar and worsening diabetic eye disease in people with type 2 diabetes. The label also lists a risk of thyroid C-cell tumors. Contact a doctor promptly about suspected serious side effects. Stop treatment if pancreatitis is suspected. If a serious allergic reaction is suspected, including anaphylaxis or swelling beneath the skin, stop treatment and seek medical attention promptly. Low blood sugar risk is higher when tirzepatide is used with insulin or medicines that stimulate insulin release. It is not recommended for people with severe delayed stomach emptying (gastroparesis). Tell your healthcare team about any planned surgery or procedure: inhalation of stomach contents into the lungs has been reported during general anesthesia or deep sedation in people receiving GLP-1 receptor agonists.
FDA boxed warning
Risk of thyroid c-cell tumors
In rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. It is unknown whether ZEPBOUND causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of tirzepatide-induced rodent thyroid C-cell tumors has not been determined
ZEPBOUND is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
. Counsel patients regarding the potential risk for MTC with the use of ZEPBOUND and inform them of symptoms of thyroid tumors (e.g., a mass in the neck, dysphagia, dyspnea, persistent hoarseness). Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with ZEPBOUND
In rats, tirzepatide causes thyroid C-cell tumors. It is unknown whether ZEPBOUND causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as the human relevance of tirzepatide-induced rodent thyroid C-cell tumors has not been determined.
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
The supplied Zepbound (tirzepatide) label lists the following contraindications: a personal or family history of medullary thyroid carcinoma (MTC), Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or a known serious allergy to tirzepatide or any ingredient in Zepbound. This label is for Zepbound, not the compounded product. Tirzepatide is not recommended for people with severe gastroparesis (severely delayed stomach emptying). Digestive side effects can sometimes be severe. Reactions that cause dehydration may lead to acute kidney injury and require kidney function monitoring. Gallbladder disease and acute pancreatitis have been reported. Suspected gallbladder inflammation requires assessment. If pancreatitis is suspected, stop treatment. If a serious allergic reaction is suspected, stop treatment and seek medical attention promptly. Low blood sugar can occur, with a higher risk, including severe episodes, when used with insulin or medicines that stimulate insulin release. Your prescriber may need to adjust these other medicines. People with type 2 diabetes and a history of diabetic retinopathy need monitoring for worsening eye disease. Tell healthcare professionals about any planned surgery or procedure. Aspiration of stomach contents into the lungs has been reported during general anesthesia or deep sedation. Tirzepatide may harm an unborn baby; stop treatment when pregnancy is recognized. If you use oral contraceptives, switch to a non-oral method or add a barrier method for 4 weeks after starting treatment and for 4 weeks after each dose increase.
Interactions
Tirzepatide delays stomach emptying, which may affect how medicines taken by mouth are absorbed. Tell your doctor about any oral medicines you take.
Using Tirzepatide Compound
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store in the original carton below 25°C, protected from light, unless the pack states refrigeration. Do not freeze. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label ZEPBOUND (TIRZEPATIDE) INJECTION, SOLUTION ZEPBOUND (TIRZEPATIDE) INJECTION, SOLUTION ZEPBOUND KWIKPEN (TIRZEPATIDE) INJECTION, SOLUTION [ELI LILLY AND COMPANY] (DailyMed, retrieved 19 September 2026).
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