Illustrative image.
Welchol
Colesevelam Hydrochloride
$335.00
625mg · 180 tablets · 6 months supply
GenericGeneric medicine
$55.83 per month
Annual cost
$670a year at this pack size
Prescription required
Upload your prescription after ordering, or send it to our pharmacy team. We dispense only against a valid prescription.
About Welchol
Overview
Welchol (colesevelam hydrochloride) is a prescription tablet used alongside diet and exercise to lower elevated LDL (“bad”) cholesterol in adults with primary hyperlipidemia and improve blood sugar control in adults with type 2 diabetes. It is also used to lower LDL cholesterol in boys and girls who have started menstruating, aged 10 to 17, with heterozygous familial hypercholesterolemia when diet and lifestyle changes have not lowered LDL enough. It binds bile acids in the digestive tract and is not absorbed into the body.
What it treats
Used alongside diet and exercise to: - Lower elevated LDL cholesterol in adults with primary hyperlipidemia. - Lower LDL cholesterol in boys and girls who have started menstruating, aged 10–17 years, with heterozygous familial hypercholesterolemia (HeFH), when an adequate trial of diet and lifestyle changes has not achieved LDL targets. - Improve blood sugar control in adults with type 2 diabetes. Not for treating type 1 diabetes or diabetic ketoacidosis.
Safety information
Side effects
Common side effects include constipation, indigestion and nausea. Serious risks include increased triglycerides (a type of blood fat), which can cause acute pancreatitis (inflammation of the pancreas). Stop taking Welchol and seek prompt medical attention if symptoms of acute pancreatitis occur. Bowel obstruction has also been reported and warrants prompt medical attention. Welchol is not recommended for people with delayed stomach emptying, other conditions affecting movement through the digestive tract, or previous major digestive tract surgery that puts them at risk of bowel obstruction. Welchol may reduce absorption of fat-soluble vitamins, including vitamin K. Contact your doctor about this risk, particularly if you take warfarin or have a condition that reduces nutrient absorption.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take Welchol if you have triglyceride levels above 500 mg/dL, a history of pancreatitis caused by high triglycerides, or a history of bowel obstruction. Welchol can raise triglyceride levels, which can cause acute pancreatitis. Blood fat levels, including triglycerides, should be monitored. Stop taking Welchol and seek prompt medical attention if symptoms of acute pancreatitis occur. Welchol is not recommended for people with delayed stomach emptying (gastroparesis), other conditions that slow movement through the digestive tract, or previous major digestive tract surgery that may put them at risk of bowel obstruction. Welchol may reduce absorption of fat-soluble vitamins. Extra caution is needed if you are prone to vitamin K or other fat-soluble vitamin deficiencies, including if you take warfarin or have a condition that reduces nutrient absorption. It may also reduce absorption of other medicines. Tell your prescriber about all medicines and vitamin supplements you take so they can advise on timing.
Interactions
Welchol may reduce the amount of certain medicines your body absorbs. Tell your doctor if you take: - Medicines with a narrow safe dosing range, such as cyclosporine - Phenytoin - Thyroid hormone replacement - Warfarin - Oral contraceptives containing ethinyl estradiol and norethindrone - Olmesartan medoxomil - Sulfonylureas, including glimepiride, glipizide or glyburide Ask your doctor how to separate these medicines from Welchol. If you take warfarin, your INR blood test will need frequent monitoring when Welchol is started, then periodic checks. Welchol may increase the amount of extended-release metformin your body absorbs. Your blood sugar control should be monitored if you take these medicines together.
Using Welchol
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label WELCHOL (COLESEVELAM HYDROCHLORIDE) TABLET, FILM COATED WELCHOL (COLESEVELAM HYDROCHLORIDE) FOR SUSPENSION [COSETTE PHARMACEUTICALS, INC.] (DailyMed, retrieved 19 September 2026).
Reviews
No reviews yet. Mail Order Drugs opened recently, and we publish reviews only from verified customers of this site, so this space stays empty until real ones arrive.
- Every prescription order is checked by a licensed pharmacist before dispensing.
- Payment pages are encrypted and card details never reach our servers.
- We ship internationally, with cold-chain packing where a medicine needs it.
Related medicines
Vascepa
Icosapent
Capsules · from 120 per pack
Also for cholesterol
Brand $503.00
Evkeeza
Evinacumab
By Ultragenyx
Vial · from 1 per pack
Also for cholesterol
Brand $15,240.00
Livalo
Pitavastatin
Tablets · from 30 per pack
Also for cholesterol
Generic from $30.00
Tricor
Fenofibrate
Capsules and Tablets · from 30 per pack
Also for cholesterol
Generic $39.00